he International Hemoglobinopathy Research Network (INHERENT) is an international network that focuses on the study of genetic modifiers for hemoglobinopathies through a large-scale multi-ethnic genome-wide association study (GWAS). To achieve its primary objective, INHERENT brings together existing international and regional consortia in the field of hemoglobinopathies, aiming at standardising phenotypic definitions and developing an open research infrastructure that will foster international collaboration for the benefit of patients and their families.
The target sample size for the envisioned GWAS was set to 30000 hemoglobinopathy patients, which will be the largest study in the field by over one order of magnitude. This will provide the opportunity to validate previously reported associations and discover new genetic modifiers for hemoglobinopathies
Participation in INHERENT is open to any group/study that can submit a minimum of 30 DNA sample for the GWAS with their core phenotypic descriptions.
For more information, visit the INHERENT website