RELEVANCE (Regulation of red cell life-span, erythropoiesis, survival, senescence and clearance) is an international consortium founded by the EU within the Marie Skłodowska-Curie Actions Program established with the objective to develop new fast and cost-effective methods for diagnosis of the underlying causes of anaemia, and to optimise treatment options for both general and personalised medicine.
RELEVANCE includes 13 partners representing academic research centres, diagnostic labs, blood supply centres, and small industries that combines basic and translational research to improve prognostic, diagnostic and therapeutic approaches on red blood cells production, function, and clearance in healthy humans and patients. Partners are based in Germany, France, UK, Italy, Switzerland, Spain, the Netherlands and Denmark, contributing to the five work packages (WP) established for the performing of the actions.
As Innovative Training Network (ITN), RELEVANCE consortium has recruited 15 early stage researchers (ESR) from all over the world who have been working in the project for three years. Each ESR has been focused in some particular topics while having the opportunity to interact within the WPs.
Since its start in September 2015, RELEVANCE project is coming to an end with valuable and promising results that will be soon disseminated. In this context, the results obtained will be the basis for the new Marie Curie - ITN EVIDENCE (Erythrocytes properties and viability in dependence of flow and extra-cellular environment) aiming to explore the properties and behaviour of RBCs under flow conditions and in vivo to understand pathophysiology and to design novel diagnostic devices.
RELEVANCE project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 675115 - RELEVANCE - H2020-MSCA-ITN-2015/H2020-MSCA-ITN-2015.